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Cannabis has grown in popularity for its effectiveness in reducing pain. Recent studies have increased our understanding of its mechanism and how it works with our bodies to reduce pain. The research is ongoing as there is scant data about the potential side effects, but the evidence so far about its ability to reduce pain is promising. Here are the reasons why cannabis reduces pain.

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  • Blocks the signals 

If you have a wound in your body, using cannabis can reduce the pain because it targets the pain signals and dampens its effect. So, cannabis stops them before they get to the brain. The abundant CBD and THC in cannabis work at the injury site and block the inflammation as both have anti-inflammatory properties.

  • Weakens the effects

Cannabis triggers the serotonin receptors, which has seen promising pain reduction results across human and rodent model clinical studies. The activation of such properties weakens the potency of pain signals in the spinal cord and the brain. When over-activated, the CB1 properties in cannabis weaken the effects of the pain signals. 

  • Interacts with receptors

When you inhale or ingest cannabis, the THC elements stimulate and bind together with the cannabinoid receptors of the brain. This process activates the reward system in the brain and reduces pain. The cannabinoid receptors naturally occurring in our bodies interact with THC to exert anti-inflammatory and pain-relieving effects.

  • Modulates pain perception

One of the main reasons why cannabis reduces pain effectively is its interaction with the endocannabinoid system of the body. The system controls the desire of our body to stay stable and balanced, also called homeostasis. It plays a crucial role in immune and neuronal cell function. This activity seems to be the principal pathway for the pain-numbing effects of marijuana

  • Hits pertinent targets

The THC and CBD in cannabis inhibit brain chemicals that cause pain-numbing effects. When these chemicals activate the nerve cells, it reduces pain. The CBD interacts with the glycine receptors in the immune system, which is the leading cause of pain. Moreover, the euphoria can help pain treatments work by hitting all pertinent targets with a light touch.

  • Provides therapeutic effects

Cannabinoids affect the enzymes and ion channels, inducing analgesia that provides therapeutic effects, including pain reduction. This mechanism inhibits the release of neuropeptides and neurotransmitters from presynaptic nerves. It also modulates neuron excitability, reduces neural inflammation, and de-escalates the pain pathways. 

Bottom line

Now that you know the reasons why cannabis reduces pain, you might be considering using them to reduce pain. If you are, we recommend consulting your physician to see what brand is apt for you because the medicinal effects vary. Your physician will be in a much better position to make a recommendation based on your treatment and pain threshold. The dosage of cannabis also makes a difference.